Tutorial 5: Alternative regional genotype-phenotype map example, with meta-analyses included3 years ago
1. Setting the metadata | 2. HMGCR (3-hydroxy-3-methylglutaryl-CoA reductase) gene region | 2.1. Meta-analysis for the chd trait | 2.2. Creating a dataset for all the traits | 2.3. Finemapping with SusieR | 2.4. Colocolisation with hypercoloc | 3. PCSK9 (proprotein convertase subtilisin/kexin type 9) gene region | 3.1. Meta-analysis for the chd trait | 3.2. Creating a dataset for all the traits | 3.3. Finemapping with SusieR | 3.4. Colocolisation with hypercoloc | 4. NPC1L1 (NPC1 like intracellular cholesterol transporter 1) gene region | 4.1. Meta-analysis for the chd trait | 4.2. Creating a dataset for all the traits | 4.3. Finemapping with SusieR | 4.4. Colocolisation with hypercoloc | 5. LPA (Lipoprotein(A)) gene region | 5.1. Meta-analysis for the chd trait | 5.2. Creating a dataset for all the traits | 5.3. Finemapping with SusieR | 5.4. Colocolisation with hypercoloc
gwasglue2 0.0.0.9000Rita Rasteiro finemap_coloc2.Rmd